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Article

Development and validation of a ligand-receptor pairs signature to predict outcome and provide a therapeutic strategy in gastric cancer.

Expert review of molecular diagnostics - 1 Jan 2000

Yang Wanli, Zhao Xinhui, Duan Lili, Niu Liaoran, Zhang Yujie, Zhou Wei, Li Yiding, Chen Junfeng, Fan Aqiang, Xie Qibin, Liu Jinqiang, Han Yu, Fan Daiming, Hong Liu

Abstract excerpt

BACKGROUND: An important factor in tumor development and progression is the tumor microenvironment (TME), which is heterogeneous. Previous studies have mainly investigated the expression profile and prognostic values of genes in gastric cancer (GC) at the cell population level but neglected the interactions and heterogeneity between cells. METHODS: The pattern of ligand-receptor (LR) interactions was delineated...

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PMID: 37248704
DOI: 10.1080/14737159.2023.2219843

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