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Article

Sex differences in outcomes of people with cystic fibrosis treated with elexacaftor/tezacaftor/ivacaftor.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Jan 2024

Wang Angela, Lee MinJae, Keller Ashley, Jian Sarah, Lowe Karen, Finklea James D, Jain Raksha

Abstract excerpt

BACKGROUND: There is a well described sex-disparity in outcomes of individuals with cystic fibrosis (CF), with females faring worse than males. Given the dramatic improvement in overall health of people with CF using CF transmembrane conductance regulator (CFTR) modulator therapy, elexacaftor/tezacaftor/ivacaftor (ETI), the sex-disparity in CF warrants re-examination. METHODS: We evaluated the effects of ETI use...

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Identifiers

PMID: 37244841
DOI: 10.1016/j.jcf.2023.05.009

Genes

CFTR

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