Article
Evidence for a causal association between psoriasis and psychiatric disorders using a bidirectional Mendelian randomization analysis in up to 902,341 individuals.
Journal of affective disorders - 15 Sept 2023
Wang Yujie, Wang Xinquan, Gu Xiaoyu, Pan Jie, Ouyang Zhen, Lin Wenrui, Zhu Wu, Wang Mi, Su Juan
Abstract excerpt
BACKGROUND: The causal association between psoriasis and psychiatric disorders remains ambiguous. OBJECTIVES: This study aimed to investigate the causal relationship between psoriasis and common psychiatric disorders using bidirectional Mendelian randomization (MR) analysis. METHODS: Major depressive disorder (MDD) (N = 217,584), bipolar disorder (N = 51,710), schizophrenia (N = 77,096), and anxiety disorder...
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