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PBP2b Mutations Improve the Growth of Phage-Resistant Lactococcus cremoris Lacking Polysaccharide Pellicle.

Applied and environmental microbiology - 28 Jun 2023

Guérin Hugo, Quénée Pascal, Palussière Simon, Courtin Pascal, André Gwenaëlle, Péchoux Christine, Costache Vlad, Mahony Jennifer, van Sinderen Douwe, Kulakauskas Saulius, Chapot-Chartier Marie-Pierre

Abstract excerpt

Lactococcus lactis and Lactococcus cremoris are Gram-positive lactic acid bacteria widely used as starter in milk fermentations. Lactococcal cells are covered with a polysaccharide pellicle (PSP) that was previously shown to act as the receptor for numerous bacteriophages of the Caudoviricetes class. Thus, mutant strains lacking PSP are phage resistant. However, because PSP is a key cell wall component,...

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Identifiers

PMID: 37222606
DOI: 10.1128/aem.02103-22
PMCID: PMC10304956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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