Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide mRNA profiling in urinary extracellular vesicles reveals stress gene signature for diabetic kidney disease

19 Apr 2023

Abstract excerpt

Urinary extracellular vesicles (uEV) are a largely unexplored source of kidney-derived mRNAs with potential to serve as a liquid kidney biopsy. We assessed ∼200 uEV mRNA samples from clinical studies by genome-wide sequencing to discover mechanisms and candidate biomarkers of diabetic kidney disease (DKD) in Type 1 diabetes (T1D) with replication in Type 1 and 2 diabetes. Sequencing reproducibly showed >10,000...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aortic aneurysm repair treatments
Share to Dialysis and Renal Disease Management
Share to Extracellular vesicles in disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37216114
DOI: 10.1016/j.isci.2023.106686

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide mRNA profiling in urinary extracellular vesicles reveals stress gene signature for diabetic kidney diseasePMID 37216114Read ↗

Urine extracellular vesicles capture kidney transcriptome and hyperglycemia linked mRNA signatures for type 1 diabetic kidney diseaseSemantic proximity Read ↗

Identification of urinary extracellular vesicles differentially expressed RNAs in diabetic nephropathy via whole-transcriptome integrated analysisSemantic proximity Read ↗

Capturing the Kidney Transcriptome by Urinary Extracellular Vesicles – from Preanalytical Obstacles to Biomarker ResearchSemantic proximity Read ↗

Extracellular vesicle-derived AEBP1 mRNA as a novel candidate biomarker for diabetic kidney diseaseSemantic proximity Read ↗

Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 DiabetesSemantic proximity Read ↗

The single-cell transcriptomic landscape of early human diabetic nephropathySemantic proximity Read ↗

Urine Proteomics Identifies Biomarkers for Diabetic Kidney Disease at Different StagesSemantic proximity Read ↗

Urine-derived renal epithelial cells for deep phenotyping and transcriptomic response to therapy in Fabry disease.Semantic proximity Read ↗

Integration of transcriptome and Mendelian randomization analyses in exploring the extracellular vesicle-related biomarkers of diabetic kidney diseaseSemantic proximity Read ↗

Single-Cell Transcriptional Landscape Reveals the Regulatory Network and Its Heterogeneity of Renal Mitochondrial Damages in Diabetic Kidney DiseaseSemantic proximity Read ↗

MicroRNAs from urinary extracellular vesicles are non-invasive early biomarkers of diabetic nephropathy in type 2 diabetes patients with the 'Asian Indian phenotype'.Semantic proximity Read ↗

Urinary extracellular vesicles. A promising shortcut to novel biomarker discoveriesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.