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Article

Activity of Sotrovimab against BQ.1.1 and XBB.1 Omicron sublineages in a hamster model

17 May 2023

Abstract excerpt

The successive emergence of SARS-CoV-2 Omicron variants has completely changed the modalities of use of therapeutic monoclonal antibodies. Recent in vitro studies indicated that only Sotrovimab has maintained partial activity against BQ.1.1 and XBB.1. In the present study, we used the hamster model to determine whether Sotrovimab retains antiviral activity against these Omicron variants in vivo. Our results show...

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PMID: 37207822
DOI: 10.1016/j.antiviral.2023.105638

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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