Ultrasensitive <scp>NGS MRD</scp> assessment in Ph+  <scp>ALL</scp> : Prognostic impact and correlation with <scp>RT‐PCR</scp> for <i>BCR::ABL1</i>

Abstract excerpt

Abstract Reverse transcription polymerase chain reaction (RT‐PCR) for BCR::ABL1 is the most common and widely accepted method of measurable residual disease (MRD) assessment in Philadelphia chromosome‐positive acute lymphoblastic leukemia (Ph+ ALL); however, RT‐PCR may not be an optimal measure of MRD in many cases of Ph+ ALL. We evaluated the clinical impact of a highly sensitive next‐generation sequencing (NGS)...

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