Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Competition between skin antimicrobial peptides and commensal bacteria in type 2 inflammation enables survival of S. aureus

1 May 2023

Abstract excerpt

During inflammation, the skin deploys antimicrobial peptides (AMPs) yet during allergic inflammation it becomes more susceptible to Staphylococcus aureus . To understand this contradiction, single-cell sequencing of Il4ra −/− mice combined with skin microbiome analysis reveals that lower production of AMPs from interleukin-4 receptor α (IL-4Rα) activation selectively inhibits survival of antibiotic-producing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Peptides and Activities
Share to Asthma and respiratory diseases
Share to Dermatology and Skin Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37167061
DOI: 10.1016/j.celrep.2023.112494

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Competition between skin antimicrobial peptides and commensal bacteria in type 2 inflammation enables survival of S. aureusPMID 37167061Read ↗

Tissue resident cells differentiate S. aureus from S. epidermidis via IL-1β following barrier disruption in healthy human skinSemantic proximity Read ↗

The Commensal Staphylococcus warneri Makes Peptide Inhibitors of MRSA Quorum Sensing that Protect Skin from Atopic or Necrotic DamageSemantic proximity Read ↗

Gram‐negative anaerobes elicit a robust keratinocytes immune response with potential insights into <scp>HS</scp> pathogenesisSemantic proximity Read ↗

Interactions between Host Immunity and Skin-Colonizing Staphylococci: No Two Siblings Are AlikeSemantic proximity Read ↗

Updated understanding of Staphylococcus aureus in atopic dermatitis: From virulence factors to commensals and clonal complexesSemantic proximity Read ↗

Staphylococcus cohnii is a potentially biotherapeutic skin commensal alleviating skin inflammationSemantic proximity Read ↗

Exploring the Role of Staphylococcus Aureus Toxins in Atopic DermatitisSemantic proximity Read ↗

PSMε controls skin commensal CD8 <sup>+</sup> T cell activationSemantic proximity Read ↗

Architecture of antimicrobial skin defenseSemantic proximity Read ↗

Gastrointestinal colonization as a source of <i>Staphylococcus aureus</i> in atopic dermatitisSemantic proximity Read ↗

Antimicrobial peptides in human skin disease.Semantic proximity Read ↗

Pathogenic role of the staphylococcal accessory gene regulator quorum sensing system in atopic dermatitisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.