Article
Front-line therapy for brain metastases and non-brain metastases in advanced epidermal growth factor receptor-mutated non-small cell lung cancer: a network meta-analysis.
Chinese medical journal - 5 Nov 2023
Zhu Yixiang, Liu Chengcheng, Xu Ziyi, Zou Zihua, Xie Tongji, Xing Puyuan, Wang Le, Li Junling
Abstract excerpt
BACKGROUND: The brain is a common metastatic site in patients with non-small cell lung cancer (NSCLC), resulting in a relatively poor prognosis. Systemic therapy with epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) is recommended as the first-line treatment for EGFR -mutated, advanced NSCLC patients. However, intracranial activity varies in different drugs. Thus, brain metastasis (BM)...
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