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Article

Evaluation of endpoints for the study and diagnosis of mitochondrial toxicity and disease: a narrative review.

Mutagenesis - 20 Jun 2023

Gharti Prashamsa, Fletcher Jessica F, Chapman Katherine E

Abstract excerpt

Mitochondrial DNA mutation and toxicity have been linked to several inherited and acquired diseases; however, these are challenging to diagnose and characterize due to clinical and genetic heterogeneity. This review investigates current techniques for the analysis of mitochondrial perturbations, and novel, emerging endpoints for routine application within the clinical setting. Particular focus is given to the...

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Identifiers

PMID: 37144479
DOI: 10.1093/mutage/gead010
PMCID: PMC10281363

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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