Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Different clinical phenotypes of a pair of siblings with familial hypercholesterolemia: a case report and literature review.

BMC cardiovascular disorders - 1 May 2023

Wang Ze-Ping, Wu Ya-Jie, Gao Ying, Qian Jie, Liu Long-Tao, Guo Yuan-Lin, Li Jian-Jun, Chen Ke-Ji

Abstract excerpt

BACKGROUND: Familial hypercholesterolemia (FH) leads to high plasma low-density lipoprotein cholesterol (LDL-C) levels and early cardiovascular morbidity and mortality. We treated a pair of siblings with FH. The cardiovascular manifestations in the proband were more severe than those in his elder sister, although they had almost similar LDL-C levels, ages, and lifestyles. Herein, we report the cases of this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol, LDL
Share to Constriction, Pathologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyperlipoproteinemia Type II

Share to Phenotype

Share to Siblings

Source

Open in PubMed Open full text

Identifiers

PMID: 37127585
DOI: 10.1186/s12872-023-03237-4
PMCID: PMC10150518

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Different clinical phenotypes of a pair of siblings with familial hypercholesterolemia: a case report and literature review.PMID 37127585Read ↗

The Clinical Importance of Differentiating Monogenic Familial Hypercholesterolemia from Polygenic HypercholesterolemiaSemantic proximity Read ↗

Guidelines for the management of familial hypercholesterolemia.Semantic proximity Read ↗

Atherosclerotic cardiovascular disease burden in patients with familial hypercholesterolemia: interpretation of data on involvement of different vascular beds.Semantic proximity Read ↗

Genetic analysis in a compound heterozygote family with familial hypercholesterolemia.Semantic proximity Read ↗

Phenotypic variability in 4 homozygous familial hypercholesterolemia siblings compound heterozygous for LDLR mutations.Semantic proximity Read ↗

[Molecular basis of familial hypercholesterolemia-like phenotype heterogeneity].Semantic proximity Read ↗

Phenotype vs. genotype in severe familial hypercholesterolemia: what matters most for the clinician?Semantic proximity Read ↗

Genetic heterogeneity of familial hypercholesterolaemia in two populations from two different countries.Semantic proximity Read ↗

Familial hypercholesterolemia and lipoprotein(a) hyperlipidemia as independent and combined cardiovascular risk factors.Semantic proximity Read ↗

[Genotype-phenotype analysis of a homozygous familial hypercholesterolemia pedigree].Semantic proximity Read ↗

High prevalence of major cardiovascular risk factors in first-degree relatives of individuals with familial premature coronary artery disease--the GENECARD project.Semantic proximity Read ↗

[Analysis of clinical phenotypes and variants of LDLR gene in two Chinese patients with familial hypercholesterolemia].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.