Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CRISPR-Cas13a-powered electrochemical biosensor for the detection of the L452R mutation in clinical samples of SARS-CoV-2 variants.

Journal of nanobiotechnology - 29 Apr 2023

Chen Zhi, Wu Chenshuo, Yuan Yuxuan, Xie Zhongjian, Li Tianzhong, Huang Hao, Li Shuang, Deng Jiefeng, Lin Huiling, Shi Zhe, Li Chaozhou, Hao Yabin, Tang Yuxuan, You Yuehua, Al-Hartomy Omar A, Wageh Swelm, Al-Sehemi Abdullah G, Lu Ruitao, Zhang Ling, Lin Xuechun, He Yaqing, Zhao Guojun, Li Defa, Zhang Han

Abstract excerpt

Since the end of 2019, a highly contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has deprived numerous lives worldwide, called COVID-19. Up to date, omicron is the latest variant of concern, and BA.5 is replacing the BA.2 variant to become the main subtype rampaging worldwide. These subtypes harbor an L452R mutation, which increases their transmissibility among vaccinated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clustered Regularly Interspaced Short Palindromic Repeats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to COVID-19

Share to Metal Nanoparticles

Share to Mutation

Share to SARS-CoV-2

Source

Open in PubMed Open full text

Identifiers

PMID: 37120637
DOI: 10.1186/s12951-023-01903-5
PMCID: PMC10148006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CRISPR-Cas13a-powered electrochemical biosensor for the detection of the L452R mutation in clinical samples of SARS-CoV-2 variants.PMID 37120637Read ↗

CRISPR-Cas12a-Empowered Electrochemical Biosensor for Rapid and Ultrasensitive Detection of SARS-CoV-2 Delta VariantSemantic proximity Read ↗

SARS-CoV-2 detection by targeting four loci of viral genome using graphene oxide and gold nanoparticle DNA biosensorSemantic proximity Read ↗

Multiplexed biosensor for point-of-care COVID-19 monitoring: CRISPR-powered unamplified RNA diagnostics and protein-based therapeutic drug managementSemantic proximity Read ↗

A CRISPR/Cas12a-empowered surface plasmon resonance platform for rapid and specific diagnosis of the Omicron variant of SARS-CoV-2Semantic proximity Read ↗

Amplification‐Free Detection of SARS‐CoV‐2 and Respiratory Syncytial Virus Using CRISPR Cas13a and Graphene Field‐Effect TransistorsSemantic proximity Read ↗

Early and Sensitive Detection of Pathogens for Public Health and Biosafety: An Example of Surveillance and Genotyping of SARS-CoV-2 in Sewage Water by Cas12a-Facilitated Portable Plasmonic BiosensorSemantic proximity Read ↗

Amplification‐Free Detection of SARS‐CoV‐2 and Respiratory Syncytial Virus Using CRISPR Cas13a and Graphene Field‐Effect TransistorsSemantic proximity Read ↗

CRISPR‐Mediated Profiling of Viral RNA at Single‐Nucleotide ResolutionSemantic proximity Read ↗

Multiplexed biosensor for point-of-care COVID-19 monitoring: CRISPR-powered unamplified RNA diagnostics and protein-based therapeutic drug managementSemantic proximity Read ↗

One-base-mismatch CRISPR-based transistors for single nucleotide resolution assay.Semantic proximity Read ↗

CRISPR‐Mediated Profiling of Viral RNA at Single‐Nucleotide ResolutionSemantic proximity Read ↗

Detection of SARS-CoV-2 by CRISPR/Cas12a-Enhanced ColorimetrySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.