Article
Gene-by-Sex Interactions: Genome-Wide Association Study Reveals Five SNPs Associated with Obesity and Overweight in a Male Population.
Genes - 26 Mar 2023
Kyrgiafini Maria-Anna, Sarafidou Theologia, Giannoulis Themistoklis, Chatziparasidou Alexia, Christoforidis Nikolaos, Mamuris Zissis
Abstract excerpt
Obesity is a chronic health problem associated with severe complications and with an increasing prevalence in the Western world. Body-fat composition and distribution are closely associated with obesity, but the human body's composition is a sexually dimorphic trait, as differences between the two sexes are evident even from fetal life. The effect of sex hormones contributes to this phenomenon. However, studies...
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