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Comparison of SARS-CoV-2 whole genome sequencing using tiled amplicon enrichment and bait hybridization

20 Apr 2023

Abstract excerpt

The severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) pandemic has led to extensive virological monitoring by whole genome sequencing (WGS). Investigating the advantages and limitations of different protocols is key when conducting population-level WGS. SARS-CoV-2 positive samples with Ct values of 14-30 were run using three different protocols: the Twist Bioscience SARS‑CoV‑2 protocol with bait...

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PMID: 37081087
DOI: 10.1038/s41598-023-33168-1

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