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m7G-related genes-NCBP2 and EIF4E3 determine immune contexture in head and neck squamous cell carcinoma by regulating CCL4/CCL5 expression.

Molecular carcinogenesis - 1 Aug 2023

Xu Xuhui, Zhao Yue, Ying Yukang, Zhu Haoran, Luo Jun, Mou Tingchen, Zhang Zhenxing

Abstract excerpt

Aberrant N7 -methylguanosine (m7G) levels closely correlate with tumor genesis and progression. NCBP2 and EIF4E3 are two important m7G-related cap-binding genes. This study aimed to identify the relationship between the EIF4E3/NCBP2 function and immunological characteristics of head and neck squamous cell carcinoma (HNSCC). Hierarchical clustering was employed in classifying HNSCC patients into two groups based...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Eukaryotic Initiation Factor-4E

Share to Gene Expression Regulation, Neoplastic

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Share to Models, Statistical

Share to Squamous Cell Carcinoma of Head and Neck

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PMID: 37067401
DOI: 10.1002/mc.23548

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