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Article

Indirect comparison of mobocertinib and real-world therapies for pre-treated non-small cell lung cancer with EGFR exon 20 insertion mutations.

Lung cancer (Amsterdam, Netherlands) - 1 May 2023

Christopoulos Petros, Prawitz Thibaud, Hong Jin-Liern, Lin Huamao M, Hernandez Luis, Jin Shu, Tan Min, Proskorovsky Irina, Lin Jianchang, Zhang Pingkuan, Patel Jyoti D, Ou Sai-Hong I, Thomas Michael, Stenzinger Albrecht

Abstract excerpt

OBJECTIVES: Mobocertinib, a novel oral epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, is available for the treatment of non-small cell lung cancer (NSCLC) with EGFR exon 20 insertion (ex20ins) mutations after platinum chemotherapy. We performed an indirect comparison of clinical trial data and real-world data (RWD) to determine the relative efficacy of mobocertinib vs. other treatments for...

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Identifiers

PMID: 37058788
DOI: 10.1016/j.lungcan.2023.107191

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