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FLK is an mRNA m6A reader that regulates floral transition by modulating the stability and splicing of FLC in Arabidopsis.

Molecular plant - 1 May 2023

Amara Umme, Hu Jianzhong, Cai Jing, Kang Hunseung

Abstract excerpt

N6-methyladenosine (m6A), which is added, removed, and interpreted by m6A writers, erasers, and readers, respectively, is the most abundant modification in eukaryotic mRNAs. The m6A marks play a pivotal role in the regulation of floral transition in plants. FLOWERING LOCUS K (FLK), an RNA-binding protein harboring K-homology (KH) motifs, is known to regulate floral transition by repressing the levels of a key...

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PMID: 37050878
DOI: 10.1016/j.molp.2023.04.005

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