Article
Mutated Isocitrate Dehydrogenase (mIDH) as Target for PET Imaging in Gliomas.
Molecules (Basel, Switzerland) - 23 Mar 2023
Neumaier Felix, Zlatopolskiy Boris D, Neumaier Bernd
Abstract excerpt
Gliomas are the most common primary brain tumors in adults. A diffuse infiltrative growth pattern and high resistance to therapy make them largely incurable, but there are significant differences in the prognosis of patients with different subtypes of glioma. Mutations in isocitrate dehydrogenase (IDH) have been recognized as an important biomarker for glioma classification and a potential therapeutic target....
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