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C9 regulates the complement-mediated cell lysis in association with CD59 to resist bacterial infection in a primary animal

5 Apr 2023

Abstract excerpt

Complement component 9 (C9), as an essential component of terminal membrane attack complex of complement system, plays an important role in innate immune defense. However, the function and regulatory mechanism of C9 in the antimicrobial immune response of teleost fish remain unclear. In this study, the open reading frame of Nile tilapia (Oreochromis niloticus) C9 (OnC9) gene was amplified. The mRNA and protein...

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PMID: 37023872
DOI: 10.1016/j.ijbiomac.2023.124317

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