Article
Comparative analysis of adjuvant therapy for stage III BRAF-mut melanoma: A real-world retrospective study from single center in China.
Cancer medicine - 1 May 2023
Zhong Jingqin, Sun Wei, Hu Tu, Wang Chunmeng, Yan Wangjun, Luo Zhiguo, Liu Xin, Xu Yu, Chen Yong
Abstract excerpt
BACKGROUND: BRAF V600 mutation is the most common oncogenic alternation in melanoma and is visible in around 50% of cutaneous and 10%-15% of acral or mucosal subtypes. Currently, immunotherapy with anti-PD-1 blockade and dual-targeted therapy with Dabrafenib plus trametinib (D + T) target therapy have been approved as adjuvant therapies for Stage III melanoma with BRAF V600 mutation. According to their phase III...
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