Article
The Risk of the Next Child Getting Affected by Chronic Granulomatous Disease in Families with at Least One Autosomal Recessive CGD Child.
Iranian journal of allergy, asthma, and immunology - 20 Feb 2023
Modarresi Seyedeh Zalfa, Tajik Shagayegh, Badalzadeh Mohsen, Fazlollahi Mohammad Reza, Houshmand Massoud, Maddah Marzieh, Alizadeh Zahra, Nabavi Mohammad, Bazargan Nasrin, Movahedi Masoud, Pourpak Zahra
Abstract excerpt
Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder more common in autosomal recessive (AR) than X-linked in Iran. This study aimed to assess whether having a child with AR-CGD would increase the likelihood of the next child being affected by CGD. Ninety-one families with at least one child affected by AR-CGD entered this study. Out of the 270 children, 128 were affected by AR-CGD. We...
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