Article
Impact of age and gender on glioblastoma onset, progression, and management.
Mechanisms of ageing and development - 1 Apr 2023
Colopi Ambra, Fuda Serena, Santi Samuele, Onorato Angelo, Cesarini Valeriana, Salvati Maurizio, Balistreri Carmela Rita, Dolci Susanna, Guida Eugenia
Abstract excerpt
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults, while its frequency in pediatric patients is 10-15%. For this reason, age is considered one of the major risk factors for the development of GBM, as it correlates with cellular aging phenomena involving glial cells and favoring the process of tumor transformation. Gender differences have been also identified, as the incidence of GBM is...
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