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Article

Deep phenotype characterization of hypertensive response to exercise: implications on functional capacity and prognosis across the heart failure spectrum.

European journal of heart failure - 1 Apr 2023

Pugliese Nicola Riccardo, De Biase Nicolò, Del Punta Lavinia, Balletti Alessio, Armenia Silvia, Buralli Simona, Mengozzi Alessandro, Taddei Stefano, Metra Marco, Pagnesi Matteo, Borlaug Barry A, Williams Bryan, Masi Stefano

Abstract excerpt

AIMS: Limited evidence is available regarding the role of hypertensive response to exercise (HRE) in heart failure (HF). We evaluated the systolic blood pressure (SBP) to workload slope during exercise across the HF spectrum, investigating haemodynamic and prognostic correlates of HRE. METHODS AND RESULTS: We prospectively enrolled 369 patients with HF Stage C (143 had preserved [HFpEF], and 226 reduced [HFrEF]...

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PMID: 36992634
DOI: 10.1002/ejhf.2827

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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