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Clinical features and outcomes of patients with diacylglycerol kinase epsilon nephropathy: a nationwide experience.

Pediatric nephrology (Berlin, Germany) - 1 Sept 2023

Khandelwal Priyanka, Thangaraju Sharan, Krishnamurthy Sriram, Ohri Alpana, Pais Priya, Mathew Georgie, Sharma Jyoti, Sharma Aditi, Hari Pankaj, Sinha Aditi, Singh Geetika, Bagga Arvind

Abstract excerpt

BACKGROUND: Thrombotic microangiopathy (TMA) is usually caused due to dysregulation of the alternative complement pathway. Rarely, thrombotic microangiopathy is caused by non-complement mediated mutations in diacylglycerol kinase epsilon (DGKE); information about therapy and outcome of these patients is limited. METHODS: Medical records of patients, younger than 18 years, diagnosed with TMA and variants in DGKE...

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PMID: 36988693
DOI: 10.1007/s00467-023-05939-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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