Article
The genetic liability to rheumatoid arthritis may decrease hepatocellular carcinoma risk in East Asian population: a Mendelian randomization study.
Arthritis research & therapy - 27 Mar 2023
Zhang Yuzhuo, Zhang Yudong, He Peng, Ge Fan, Huo Zhenyu, Qiao Guibin
Abstract excerpt
BACKGROUND: Patients with rheumatoid arthritis (RA) have a rising possibility of acquiring certain kinds of cancers than the general public. The causal risk association between RA and hepatocellular carcinoma (HCC) remains unknown. METHODS: Genetic summary data from genome-wide association study (GWAS), including RA (n = 19,190) and HCC (n = 197,611), was analyzed. The inverse-variance weighted (IVW) approach was...
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