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Article

Identification of circRNA-miRNA-mRNA regulatory network and its role in cardiac hypertrophy

23 Mar 2023

Abstract excerpt

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is a grave hazard to human health. Circular RNA (circRNAs) and micro RNA (miRNAs), which are competitive endogenous RNA, have been shown to play a critical role inHCM pathogenicity. However, to a great extent, the biological activities of ceRNA in HCM pathophysiology and prognosis remain to be investigated. MATERIALS AND METHODS: By analyzing the expression files in...

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PMID: 36952519
DOI: 10.1371/journal.pone.0279638

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