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Article

Identification of cuproptosis-related subtypes and the development of a prognostic model in glioma

1 Mar 2023

Abstract excerpt

Introduction: A copper-dependent cell death, cuproptosis, involves copper binding with lipoylated tricarboxylic acid (TCA) cycle components. In cuproptosis, ferredoxin 1 (FDX1) and lipoylation act as key regulators. The mechanism of cuproptosis differs from the current knowledge of cell death, which may invigorate investigations into copper’s potential as a cancer treatment. An extremely dismal prognosis is...

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Identifiers

PMID: 36936439
DOI: 10.3389/fgene.2023.1124439

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