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Article

Identification of a novel cuproptosis-related gene signature and integrative analyses in patients with lower-grade gliomas.

Frontiers in immunology - 1 Jan 2022

Bao Jia-Hao, Lu Wei-Cheng, Duan Hao, Ye Ya-Qi, Li Jiang-Bo, Liao Wen-Ting, Li Yong-Chun, Sun Yang-Peng

Abstract excerpt

Background: Cuproptosis is a newly discovered unique non-apoptotic programmed cell death distinguished from known death mechanisms like ferroptosis, pyroptosis, and necroptosis. However, the prognostic value of cuproptosis and the correlation between cuproptosis and the tumor microenvironment (TME) in lower-grade gliomas (LGGs) remain unknown. Methods: In this study, we systematically investigated the genetic and...

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Identifiers

PMID: 36045691
DOI: 10.3389/fimmu.2022.933973
PMCID: PMC9420977

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