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Ten-point guide on the management of healthy women carrying BRCA1/2 mutations.

Maturitas - 1 May 2023

Caretto Marta, Casula Elisa, Catrambone Ilaria, Giannini Andrea, Simoncini Tommaso

Abstract excerpt

Healthy women carrying pathogenic germline mutations in BRCA1 or BRCA2 genes have an increased risk of breast and ovarian cancer. Prophylactic gynecological surgery includes risk-reducing bilateral salpingo-oophorectomy, which, in selected cases, can be combined with hysterectomy. Prophylactic gynecological surgery is recommended after completion of childbearing and can be performed for women aged 35 or more for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36930999
DOI: 10.1016/j.maturitas.2023.02.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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