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Association of SARS-CoV-2 BA.4/BA.5 Omicron lineages with immune escape and clinical outcome

14 Mar 2023

Abstract excerpt

Expansion of the SARS-CoV-2 BA.4 and BA.5 Omicron subvariants in populations with prevalent immunity from prior infection and vaccination, and associated burden of severe COVID-19, has raised concerns about epidemiologic characteristics of these lineages including their association with immune escape or severe clinical outcomes. Here we show that BA.4/BA.5 cases in a large US healthcare system had at least 55%...

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PMID: 36918548
DOI: 10.1038/s41467-023-37051-5

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