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Article

Unusual Talaromyces marneffei and Pneumocystis jirovecii coinfection in a child with a STAT1 mutation: A case report and literature review.

Frontiers in immunology - 1 Jan 2023

Yang Qin, Yu Chendi, Wu Yue, Cao Ke, Li Xiaonan, Cao Weiguo, Cao Lichao, Zhang Shenrui, Ba Ying, Zheng Yuejie, Zhang Hezi, Wang Wenjian

Abstract excerpt

Talaromyces marneffei and Pneumocystis jirovecii are the common opportunistic pathogens in immunodeficient patients. There have been no reports of T. marneffei and P. jirovecii coinfection in immunodeficient children. Signal transducer and activator of transcription 1 (STAT1) is a key transcription factor in immune responses. STAT1 mutations are predominately associated with chronic mucocutaneous candidiasis and...

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Identifiers

PMID: 36891307
DOI: 10.3389/fimmu.2023.1103184
PMCID: PMC9986280

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