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Article

Bufalin reverses ABCB1-mediated resistance to docetaxel in breast cancer

20 Feb 2023

Abstract excerpt

Background Docetaxel (DCT) is widely used in clinical practice, but the drug resistance of breast cancer patients has become an important reason to limit its clinical efficacy. Chan'su is a commonly used traditional Chinese medicine for the treatment of breast cancer. Bufalin (BUF) is a bioactive polyhydroxy steroid extracted from chan'su and has strong antitumor activity, but there are few studies on reversing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36879978
DOI: 10.1016/j.heliyon.2023.e13840

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