Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic Association Study Uncovered H3K27 Acetylation Enhancers and Dysregulated Genes in High-Fat-Diet-Induced Nonalcoholic Fatty Liver Disease in Rats

1 Dec 2022

Abstract excerpt

Aim: To evaluate the regulatory landscape underlying the active enhancer marked by H3K27ac in high-fat diet (HFD)-induced nonalcoholic fatty liver disease (NAFLD) in rats. Materials & methods: H3K27ac chromatin immunoprecipitation and high-throughput RNA sequencing to construct regulatory profiles and transcriptome of liver from NAFLD rat model induced by HFD. De novo motif analysis for differential H3K27ac...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Endoplasmic Reticulum Stress and Disease
Share to Liver Disease Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36851897
DOI: 10.2217/epi-2022-0362

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic Association Study Uncovered H3K27 Acetylation Enhancers and Dysregulated Genes in High-Fat-Diet-Induced Nonalcoholic Fatty Liver Disease in RatsPMID 36851897Read ↗

Dysregulated H3K27 Acetylation Is Implicated in Fatty Liver Hemorrhagic Syndrome in ChickensSemantic proximity Read ↗

Genetic and Epigenetic Regulation in Nonalcoholic Fatty Liver Disease (NAFLD).Semantic proximity Read ↗

Genetic and Epigenetic Fine Mapping of Complex Trait Associated Loci in the Human LiverSemantic proximity Read ↗

Genome‐Wide Profiling of H3K27ac Identifies TDO2 as a Pivotal Therapeutic Target in Metabolic Associated Steatohepatitis Liver DiseaseSemantic proximity Read ↗

Mechanism and Therapeutic Opportunities of Histone Modifications in Chronic Liver DiseaseSemantic proximity Read ↗

The Chromatin Accessibility Landscape of Nonalcoholic Fatty Liver Disease ProgressionSemantic proximity Read ↗

Histone Modifications in NAFLD: Mechanisms and Potential TherapySemantic proximity Read ↗

Integrated Multiomic Analysis Reveals the High-Fat Diet Induced Activation of the MAPK Signaling and Inflammation Associated Metabolic Cascades via Histone Modification in Adipose TissuesSemantic proximity Read ↗

Epigenetic regulation of H3K27me3 in laying hens with fatty liver hemorrhagic syndrome induced by high-energy and low-protein dietsSemantic proximity Read ↗

Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver diseaseSemantic proximity Read ↗

Epigenetic regulation of H3K27me3 in laying hens with fatty liver hemorrhagic syndrome induced by high-energy and low-protein dietsSemantic proximity Read ↗

Unraveling the relationship between histone methylation and nonalcoholic fatty liver diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.