Article
Duck Circovirus genotype 2 ORF3 protein induces apoptosis through the mitochondrial pathway.
Poultry science - 1 Apr 2023
Huang Juan, Zhang Yanting, Cheng Anchun, Wang Mingshu, Liu Mafeng, Zhu Dekang, Chen Shun, Zhao Xinxin, Yang Qiao, Wu Ying, Zhang Shaqiu, Ou Xumin, Mao Sai, Gao Qun, Sun Di, Tian Bin, Yin Zhongqiong, Jia Renyong
Abstract excerpt
Duck circovirus genotype 2 (DuCV2) belongs to the genus Circovirus, family Circoviridae. It can generally cause lymphocyte atrophy and necrosis in ducks, which leads to immunosuppression. The function of the DuCV2 open reading frame 3 (ORF3) protein in viral pathogenesis in host cells remains unclear. Therefore, a series of studies based on ORF3 of the isolate DuCV GH01 strain (belonging to DuCV2) were carried...
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