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Detection and identification of fungi in the lower airway of children with and without cystic fibrosis

9 Feb 2023

Abstract excerpt

Introduction Airway infection and inflammation lead to the progression of obstructive lung disease in persons with cystic fibrosis (PWCF). However, cystic fibrosis (CF) fungal communities, known drivers of CF pathophysiology, remain poorly understood due to the shortcomings of traditional fungal culture. Our objective was to apply a novel small subunit rRNA gene (SSU-rRNA) sequencing approach to characterize the...

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PMID: 36846802
DOI: 10.3389/fmicb.2023.1119703

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