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The Intracellular Amastigote of Trypanosoma cruzi Maintains an Actively Beating Flagellum

22 Feb 2023

Abstract excerpt

Understanding the interplay between intracellular pathogens and their hosts is vital to the development of new treatments and preventive strategies. The intracellular "amastigote" stage of the Chagas disease parasite, Trypanosoma cruzi, is a critical but understudied parasitic life stage. Previous work established that cytosolically localized T. cruzi amastigotes engage physically and selectively with host...

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PMID: 36840555
DOI: 10.1128/mbio.03556-22

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