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Article

Dihydromyricetin suppresses tumor growth via downregulation of the EGFR/Akt/survivin signaling pathway.

Journal of biochemical and molecular toxicology - 1 Jun 2023

Li Xiaoying, Zhou Li, Wang Ruike, Zhang Yangnan, Li Wei

Abstract excerpt

Deregulation of epidermal growth factor receptor (EGFR) signaling is frequently observed in non-small cell lung cancer (NSCLC). The present study aimed to determine the impact of dihydromyricetin (DHM) on NSCLC, a natural compound extracted from Ampelopsis grossedentata with various pharmacological activities. Results of the present study demonstrated that DHM may act as a promising antitumor agent for NSCLC...

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PMID: 36807944
DOI: 10.1002/jbt.23328

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