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Article

Impact of nucleic acid extraction procedures on human papillomavirus (HPV) detection and genotyping.

Journal of medical virology - 1 Feb 2023

Naegele Klaudia, Weissbach Fabian H, Leuzinger Karoline, Gosert Rainer, Bubendorf Lukas, Hirsch Hans H

Abstract excerpt

Human papillomavirus (HPV) infections are often asymptomatic, but some of the >200 HPV genotypes confer a high risk for precancerous cervical lesions and cervical cancer. Current clinical management of HPV infections relies on reliable nucleic acid testing detection and genotyping. We prospectively compared nucleic acid extraction without and with prior centrifugation enrichment for detecting and genotyping HPV...

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Identifiers

PMID: 36794677
DOI: 10.1002/jmv.28583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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