Article
Whole-genome single molecule real-time sequencing of SARS-CoV-2 Omicron.
Journal of medical virology - 1 Feb 2023
Nicot Florence, Trémeaux Pauline, Latour Justine, Carcenac Romain, Demmou Sofia, Jeanne Nicolas, Ranger Noémie, De Smet Clémentine, Raymond Stéphanie, Dimeglio Chloé, Izopet Jacques
Abstract excerpt
New variants and genetic mutations of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome can only be identified using accurate sequencing methods. Single molecule real-time (SMRT) sequencing has been used to characterize Alpha and Delta variants, but not Omicron variants harboring numerous mutations in the SARS-CoV-2 genome. This study assesses the performance of a target capture SMRT...
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