Article
Mutant-RB1 circulating tumor DNA in the blood of unilateral retinoblastoma patients: What happens during enucleation surgery: A pilot study.
PloS one - 1 Jan 2023
Abramson David H, Mandelker Diana L, Brannon A Rose, Dunkel Ira J, Benayed Ryma, Berger Michael F, Arcila Maria E, Ladanyi Marc, Friedman Danielle Novetsky, Jayakumaran Gowtham, Diosdado Monica S, Robbins Melissa A, Haggag-Lindgren Dianna, Shukla Neerav, Walsh Michael F, Kothari Prachi, Tsui Dana W Y, Francis Jasmine H
Abstract excerpt
Cell free DNA (cfDNA) and circulating tumor cell free DNA (ctDNA) from blood (plasma) are increasingly being used in oncology for diagnosis, monitoring response, identifying cancer causing mutations and detecting recurrences. Circulating tumor RB1 DNA (ctDNA) is found in the blood (plasma) of retinoblastoma patients at diagnosis before instituting treatment (naïve). We investigated ctDNA in naïve unilateral...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.