Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell‐free DNA profiling in retinoblastoma patients with advanced intraocular disease: An MSKCC experience

7 Jul 2020

Abstract excerpt

PURPOSE: The enucleation rate for retinoblastoma has dropped from over 95% to under 10% in the past 10 years as a result of improvements in therapy. This reduces access to tumor tissue for molecular profiling, especially in unilateral retinoblastoma, and hinders the confirmation of somatic RB1 mutations necessary for genetic counseling. Plasma cell-free DNA (cfDNA) has provided a platform for noninvasive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to DNA Repair Mechanisms
Share to Ocular Oncology and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32633890
DOI: 10.1002/cam4.3144

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell‐free DNA profiling in retinoblastoma patients with advanced intraocular disease: An MSKCC experiencePMID 32633890Read ↗

Molecular diagnosis of retinoblastoma by circulating tumor DNA analysis.Semantic proximity Read ↗

Establishing the Clinical Utility of ctDNA Analysis for Diagnosis, Prognosis, and Treatment Monitoring of Retinoblastoma: The Aqueous Humor Liquid BiopsySemantic proximity Read ↗

Genetic Diagnosis of Retinoblastoma Using Aqueous Humour—Findings from an Extended CohortSemantic proximity Read ↗

Cell Free DNA (cfDNA) in the Blood of Retinoblastoma Patients The Robert M. Ellsworth Lecture.Semantic proximity Read ↗

Tumor DNA sampling from aqueous humor in retinoblastoma - A report from South Asia.Semantic proximity Read ↗

The Potential of Aqueous Humor Sampling in Diagnosis, Prognosis, and Treatment of RetinoblastomaSemantic proximity Read ↗

Aqueous Humor Liquid Biopsy Enables Multi-Omics Tumor Profiling and Methylation-Based Machine-Learning Stratification of RetinoblastomaSemantic proximity Read ↗

Simultaneous identification of clinically relevant RB1 mutations and copy number alterations in aqueous humor of retinoblastoma eyes.Semantic proximity Read ↗

Aqueous Humor as a Liquid Biopsy for Retinoblastoma: Clear Corneal Paracentesis and Genomic AnalysisSemantic proximity Read ↗

Simultaneous Copy Number Alteration and Single-Nucleotide Variation Analysis in Matched Aqueous Humor and Tumor Samples in Children with RetinoblastomaSemantic proximity Read ↗

Liquid biopsy in Retinoblastoma: A review.Semantic proximity Read ↗

Genomic cfDNA Analysis of Aqueous Humor in Retinoblastoma Predicts Eye Salvage: The Surrogate Tumor Biopsy for RetinoblastomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.