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Optimization and Developmental Validation of 38-plex InDel Panel for Ancestry Inference.

Fa yi xue za zhi - 25 Oct 2022

Wang Qing-Guo, Zhao Lei, Li Tang-Song, Fu Wang, Xie He-Xin, Ma Yuan, Sun Wen-Ping, Han Jun-Ping

Abstract excerpt

OBJECTIVES: The previously established 38-plex InDel system was optimized and its performance was validated according to the Scientific Working Group on DNA Analysis Method (SWGDAM) application guidelines. The ancestry inference accuracy of individuals from East Asian, European, African and mixed populations was verified. METHODS: DNA standard sample 9947A was used as the template to establish the optimal...

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PMID: 36727178
DOI: 10.12116/j.issn.1004-5619.2021.510105

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