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Article

Relationship between leptin gene variants (-2548G>A and 19A>G) and obesity among north Indian Punjabi population.

Journal of genetics - 1 Jan 2023

Kaur Harjit, Bains Veena, Sharma Tanmayi, Badaruddoza

Abstract excerpt

Leptin is an adipocyte-secreted hormone which is involved in the regulation of food intake and energy expenditure. To ascertain the potential association between leptin gene (LEP) -2548G>A and 19A>G polymorphisms and obesity risk in the north Indian Punjabi population, a group of 250 obese and 300 control subjects were randomly selected. Both the polymorphisms in the LEP gene -2548G>A (GG vs AA: odds ratio (OR),...

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PMID: 36722225

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