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Article

The unique structural characteristics of the Kir 7.1 inward rectifier potassium channel: a novel player in energy homeostasis control.

American journal of physiology. Cell physiology - 1 Mar 2023

Hernandez Ciria C, Gimenez Luis E, Dahir Naima S, Peisley Alys, Cone Roger D

Abstract excerpt

The inward rectifier potassium channel Kir7.1, encoded by the KCNJ13 gene, is a tetramer composed of two-transmembrane domain-spanning monomers, closer in homology to Kir channels associated with potassium transport such as Kir1.1, 1.2, and 1.3. Compared with other channels, Kir7.1 exhibits small unitary conductance and low dependence on external potassium. Kir7.1 channels also show a phosphatidylinositol...

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Source

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Identifiers

PMID: 36717105
DOI: 10.1152/ajpcell.00335.2022
PMCID: PMC10026989

Genes

KCNJ13
MC4R

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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