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African swine fever virus transmembrane protein pEP84R guides core assembly

30 Jan 2023

Abstract excerpt

African swine fever virus (ASFV) causes a devastating hemorrhagic disease with worldwide circulation and no widely available therapeutic prevention. The infectious particle has a multilayered architecture that is articulated upon an endoplasmic reticulum (ER)-derived inner envelope. This membrane acts as docking platform for the assembly of the outer icosahedral capsid and the underlying core shell, a bridging...

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PMID: 36716344
DOI: 10.1371/journal.ppat.1011136

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