Article
Intestinal dysbiosis exacerbates the pathogenesis of psoriasis-like phenotype through changes in fatty acid metabolism.
Signal transduction and targeted therapy - 30 Jan 2023
Zhao Qixiang, Yu Jiadong, Zhou Hong, Wang Xiaoyan, Zhang Chen, Hu Jing, Hu Yawen, Zheng Huaping, Zeng Fanlian, Yue Chengcheng, Gu Linna, Wang Zhen, Zhao Fulei, Zhou Pei, Zhang Haozhou, Huang Nongyu, Wu Wenling, Zhou Yifan, Li Jiong
Abstract excerpt
The intestinal microbiota has been associated with host immunity as well as psoriasis; however, the mechanism of intestinal microbiota regulating psoriasis needs to be demonstrated systematically. Here, we sought to examine its role and mechanism of action in the pathogenesis of psoriasis. We found that the severity of psoriasis-like skin phenotype was accompanied by changes in the composition of the intestinal...
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