Article
Elevated ratio of C-type lectin-like receptor 2 level and platelet count (C2PAC) aids in the diagnosis of post-operative venous thromboembolism in IDH-wildtype gliomas.
Thrombosis research - 1 Mar 2023
Ando Kazuhiro, Natsumeda Manabu, Kawamura Masahide, Shirakawa Kamon, Okada Masayasu, Tsukamoto Yoshihiro, Eda Takeyoshi, Watanabe Jun, Saito Shoji, Takahashi Haruhiko, Kakita Akiyoshi, Oishi Makoto, Fujii Yukihiko
Abstract excerpt
INTRODUCTION: Podoplanin (PDPN) is known to induce platelet aggregation via interacting with the C-type lectin-like receptor-2 on platelets and is involved in postoperative venous thromboembolism (VTE) formation. In this study, we investigate the correlation between soluble C-type lectin-like receptor (sCLEC-2) levels and PDPN expression in patients with high grade gliomas and the relationship between sCLEC-2...
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