Article
Phenotype-specific signatures of systems-level gut microbiome associated with childhood airway allergies.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Jan 2023
Chiu Chih-Yung, Chang Ko-Chun, Chang Lun-Ching, Wang Chia-Jung, Chung Wen-Hung, Hsieh Wen-Ping, Su Shih-Chi
Abstract excerpt
BACKGROUND: Perturbation of gut symbiosis has been linked to childhood allergic diseases. However, the underlying host-microbe interaction connected with specific phenotypes is poorly understood. METHODS: To address this, integrative analyses of stool metagenomic and metabolomic profiles associated with IgE reactions in 56 children with mite-sensitized airway allergies (25 with rhinitis and 31 with asthma) and 28...
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