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Article

Molecular Evolution of RNA-Dependent RNA Polymerase Region in Norovirus Genogroup I.

Viruses - 5 Jan 2023

Zhou Nan, Huang Yue, Zhou Lu, Li Mingma, Jin Hui

Abstract excerpt

Norovirus is the leading viral agent of gastroenteritis in humans. RNA-dependent RNA polymerase (RdRp) is essential in the replication of norovirus RNA. Here, we present a comprehensive evolutionary analysis of the norovirus GI RdRp gene. Our results show that the norovirus GI RdRp gene can be divided into three groups, and that the most recent common ancestor was 1484. The overall evolutionary rate of GI RdRp is...

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Identifiers

PMID: 36680206
DOI: 10.3390/v15010166
PMCID: PMC9861054

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