A Computer Simulation of SARS-CoV-2 Mutation Spectra for Empirical Data Characterization and Analysis.

doi:10.3390/biom13010063

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Article

A Computer Simulation of SARS-CoV-2 Mutation Spectra for Empirical Data Characterization and Analysis.

Biomolecules - 28 Dec 2022

Xiao Ming, Ma Fubo, Yu Jun, Xie Jianghang, Zhang Qiaozhen, Liu Peng, Yu Fei, Jiang Yuming, Zhang Le

Abstract excerpt

It is very important to compute the mutation spectra, and simulate the intra-host mutation processes by sequencing data, which is not only for the understanding of SARS-CoV-2 genetic mechanism, but also for epidemic prediction, vaccine, and drug design. However, the current intra-host mutation analysis algorithms are not only inaccurate, but also the simulation methods are unable to quickly and precisely predict...

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PMID: 36671448
DOI: 10.3390/biom13010063
PMCID: PMC9855923

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.